#### Title: Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs #### Authors: David Juan, Juliane Perner, Enrique Carrillo de Santa Pau, Simone Marsili, David Ochoa, Ho-Ryun Chung, Martin Vingron, Daniel Rico and Alfonso Valencia. #### Citation: doi: http://dx.doi.org/10.1101/008821 ## In http://epistemnet.bioinfo.cnio.es/download/ is included all the supplementary material generated in the manuscript ## The repository is organized as follows: ChromNets - Includes the figures for the 15 ChromNets defined in the manuscript and the cytoscape session to generate the figures bam_files - The alignments in bam format for all the ChIP-Seq data used in the study coevolution - Distance evolutionary matrix mESC_CNIO_hub2 - Files for the UCSC Trackhub (http://genome.ucsc.edu/cgi-bin/hgTracks?db=mm9&hubUrl=http://epistemnet.bioinfo.cnio.es/download/mESC_CNIO_hub2/hub.txt) others - File with ChIP-Seq peaks used to extract the ChromNets from the co-location network and genome-wide location data ## Additional Information with the source code is available at https://github.com/ChromatinNetwork ## EpiStemNet web interface: visualization of co-location networks in ESCs is available at http://epistemnet.bioinfo.cnio.es/ ## UCSC Trackhub with chromatin states, cytosine modifications, histone marks and Chromatin related proteins peaks is available at http://genome.ucsc.edu/cgi-bin/hgTracks?db=mm9&hubUrl=http://epistemnet.bioinfo.cnio.es/download/mESC_CNIO_hub2/hub.txt