EpiStemNet
Welcome to EpiStemNet, the epigenetic communication network of mouse ESCs. This network was inferred from genome-wide location data (77 different epigenomic features) combined with extensive manual curation. The network is based on a communication model in which histone and cytosine modifications are considered epigenetic signals, while chromatin-associated proteins (CrPs) act as emitters or receivers of these signals. This website allows to interactively visualize the network of epigenetic communication, as well as to inspect the most relevant sub-networks (Chromnets) with links to associated resources.
Reference
- Juan D, Perner J., Carrillo de Santa Pau E., Marsili S., Ochoa D., Ho-Ryun Chung, Vingron M., Rico D., Valencia A. Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs. [Cell Reports]
Additional information
- UCSC Trackhub (Chromatin states, Cytosine modifications, Histone marks and Chromatin related protein peaks)
- Source code
- Raw files for network inference and evolutionary analysis
Simulating Layout. One moment please...
